教师名录

汪海燕副研究员硕士生导师
所在院系:机械设计工程系
办公室:机械学院355
电话:
邮箱:haiyanwang@seu.edu.cn
个人简介

汪海燕,专职副研究员/硕士生导师


主要研究方向:

1.生物芯片制备,包括基于微米和纳米级生物传感界面的新型生物芯片设计、开发、制备和测试。

2.微纳传感,包手微纳流体设计和动力学模型构建。

3.精准诊疗芯片开发,针对“卡脖子”问题,面向临床需求开发快速诊断核心技术。

4. 蛋白质测序技术,包括纳米孔单分子测序技术的开发和控制技术。


科研方面:

近年来发表论文22篇,授权专利1项。包括主要包括Chem. Commun.Anal. Chem.ACS Sensor. 担任Result in Chemistry的专刊编辑和多个学术期刊的审稿专家,包括专业领域一区期刊Chemical ScienceACS Sensors

学习经历
工作经历

2019.12-至今         248cc永利集团官网线路   248cc永利集团官网线路   专职副研究员   

2015.02- 2019.10     美国国家标准与技术研究所     Guest Researhcer   

 


教授课程
本科毕业设计


研究方向
生物芯片,微纳传感,精准诊疗,可穿戴传感器
审稿期刊

Chemical Science

ACS Sensors

Analytical Chemistry



学术兼职

Guest Editor of Results in Chemistry


获奖情况

2013.10 华东理工大学“研究生国家奖学金”

2013.04 华东理工大学“2013年度优秀博士毕业生”   

2012.10 华东理工大学“优秀学生干部”   

2012.10 华东理工大学“优秀社会工作奖一等奖”   

2011.12 华东理工大学“高水平论文奖”   

2010.10 华东理工大学计划外奖学金:天鼎东岳一等奖   



论文著作

1.       Wang H.-Y.*,Liu Y.*Near Infrared Light-Activatable Platelet-Mimicking NIR-II NONano-Prodrug for Precise Atherosclerosis Theranostics. Adv. Sci., in Proof.

2.       Hui Yu, Yun Chai, Aliya Tiemuer,Yuxuan Han, H.-Y. Wang*, Yi Liu*, Frequency upconversion luminescence:New frontiers in bioapplications, Coord. Chem. Rev., 2023, 496, 215379.

3.       Zhao C., Zhou F., Lu K. Yang S., TanB., Sun W., Shangguan L., Wang H.-Y.*, Liu Y.*, Near-infraredfluorescent probe for in vivo monitoring acetylcholinesterase activity. Sens.Actuators B: Chem. 2022, 360, 131647.

4.       Liu W., Yao X., Zhu W., Wang J.,Zhou F., Qian X., Tiemuer A., Yang S., Wang H.-Y.*, Liu Y., Azo-BasedHypoxia-Responsive Self-Assembly Near-Infrared Fluorescent Nanoprobe for InVivo Real-Time Bioimaging of Tumors. ACS Appl. Bio Mater.2021,4, 3, 2752–2758.

5.       Yu H.,Sun W., Tiemuer A., Zhang Y., Wang H.-Y. *, Liu Y.*,Mitochondria targeted near-infrared chemodosimeter for upconversionluminescence bioimaging of hypoxia.Chem. Commun., 2021,57, 5207-5210.

6.        Qian X., Zhu W., Yu H., Xu Y., Liu W., Wang H.-Y. *, LiuY.*, Mitochondria-targeted near-infrared fluorescent probe for monitoring of aCopper(I) in living cells and In vivo.Dyes and Pigments, 2021, 194,109561.

7.       Zhu W.,Qian X., Wang J., Yu H., Liu W., Wang H.-Y.*, Liu Y.*, Near-infraredfrequency upconversion probes for monitoring glutathione S-transferase toevaluate acute liver injury. Sens. Actuators B: Chem.2021, 347,130640.

8.       Zhu W., Yu H., Qian X., Lu K., Zhao C., Zhang Y., Wang H.-Y.*, Liu Y.*, Near-infraredfrequency upconversion probe for revealing the relationship between glutathioneS-transferase and drug-resistance. Anal. Chim. Acta. 2021, 1181, 338920

9.        WangH.-Y., Kasianowicz J. J., Robertson, J.W.F., PosterL. D., and Ettedgui, J., A Comparison of Ion Channel Current Blockades Causedby Individual Poly (ethylene glycol) Molecules and PolyoxometalateNanoclusters.  The Euro. Phys. J. E.2019,42 (6),83.

10.     Wang H.-Y., ZhangH., Chen S., Liu Y.*, Fluorescein-Inspired Near-Infrared Chemodosimeter forLuminescence Bioimaging. Current med. Chem.2019, 26 (21),4029-4041

11.       Wang H.-Y., Ettedgui, J., Forstater, J.H.,Robertson, J.W.F., Reiner J. E., Zhang H., Chen S.,Kasianowicz, J.J. Determining the physical properties ofmolecules with nanometer-scale pores. ACSSens.2018, 3, 251-263.

12.      Liu Y.,Yao X.-F. & Wang H.-Y.*, ProteinDetection Though Single Molecule Nanopore. Chin.J. Anal. Chem.2018, 46,6, e1838-e1846.

13.      Wang, H.-Y.,Song, Z.-Y., Zhang, H.-S., & Chen, S.-P. Single-molecule analysis of lead(II)-binding aptamer conformational changes in an α-hemolysin nanopore, andsensitive detection of lead (II). Microchim.Acta2016, 183,1003-1010.

14.      Wang, H.-Y.,Gu, Z., Wang, J., & Long, Y.-T. Analysis of a single α-synucleinfibrillation by the interaction with a protein nanopore. Analy. Chem.2013, 85,8254-8261.

15.      Wang, H.-Y.,Li, Y., Qin, L.-X., Heyman, A., Shoseyov, O., Willner, I., Long, Y.-T., &Tian, H. Single-molecule DNA detection using a novel SP1 protein nanopore. Chem. Commun.2013, 49, 1741-1743.

16.      Wang, H.-Y.,Ying, Y.-L., Li, Y., Kraatz, H.B., & Long, Y.-T. Nanopore analysis ofβ-amyloid peptide aggregation transition induced by small molecules. Anal. Chem.2011, 83, 1746-1752.

17.      Wang, H.-Y.,Ying, Y.-L., Li, Y., & Long, Y.-T. Peering into Biological Nanopore: APractical Technology to Single‐Molecule Analysis. Chem. An Asian J.2011, 5, 952-1961.

18.      LiuY., Wang S., Ma Y., J Lin, Wang H.-Y.,Gu Y., Chen X., Huang P. Ratiometric photoacoustic molecular imaging formethylmercury detection in living subjects. AdvancedMater. 2017, 29, 1606129.

19.      Kasianowicz,J.J., Balijepalli, A.K., Ettedgui, J., Forstater, J.H., Wang, H.-Y., Zhang, H.,& Robertson, J.W.F.  Analyticalapplications for pore-forming proteins. Biochim.Biophy. Acta – Biomembran.2016, 1858, 593-606.

20.      Ying,Y.-L., Wang, H.-Y. Sutherland, T.C. & Long, Y.-T. Monitoring of anATP‐Binding Aptamer and its Conformational Changes Using an a-HemolysinNanopore. Small2011, 1, 87-94.

21.      Liu,Y., Ying, Y.-L., Wang, H.-Y., Cao, C., Li, D.-W., Zhang,W.-Q., & Long, Y.-T. Real-time monitoring of the oxidative response of amembrane–channel biomimetic system to free radicals. Chem. Commun.2013, 49, 6584-6586.

22.      Liu,T., Bao, C., Wang, H.-Y., Lin, Y., Jia, H., & Zhu, L.Light-controlled ion channels formed by amphiphilic small molecules regulateion conduction viacistransphotoisomerization. Chem. Commun.2013, 49, 10311-10313.

23.       喻皓,汪海燕,龙亿涛基于LabVIEW的纳米通道单分子检测系统,授权专利号:ZL2010 2 0169643.6



科研项目

2020.01-2020.12, 项目主持人,中央高校基本业务费基础科研扶持项目-理工类:基于纳米孔的生物仿生界面机械性能研究(2242020K40221

2014.09-2016.12, 项目主持人中国博士后科学基金第56批一等资助项目:纳米通道用于核酸适配体单分子识别行为研究(2014M560670

2021.01-2024.12  项目参与人,国家自然科学基金面上项目:固态纳米孔核酸检测的关键技术和机理 (52075099)



专利

喻皓,汪海燕,龙亿涛等基于LabVIEW的纳米通道单分子检测系统,授权专利号:ZL 2010 2 0169643.6

汪海燕 生物芯片设计与制备
Tel:
Email:haiyanwang@seu.edu.cn
Add:
Personal Introduction

汪海燕,专职副研究员/硕士生导师


主要研究方向:

1.生物芯片制备,包括基于微米和纳米级生物传感界面的新型生物芯片设计、开发、制备和测试。

2.微纳传感,包手微纳流体设计和动力学模型构建。

3.精准诊疗芯片开发,针对“卡脖子”问题,面向临床需求开发快速诊断核心技术。

4. 蛋白质测序技术,包括纳米孔单分子测序技术的开发和控制技术。


科研方面:

近年来发表论文22篇,授权专利1项。包括主要包括Chem. Commun.Anal. Chem.ACS Sensor. 担任Result in Chemistry的专刊编辑和多个学术期刊的审稿专家,包括专业领域一区期刊Chemical ScienceACS Sensors

Educational Background

1.       Wang H.-Y.*,Liu Y.*Near Infrared Light-Activatable Platelet-Mimicking NIR-II NONano-Prodrug for Precise Atherosclerosis Theranostics. Adv. Sci., in Proof.

2.       Hui Yu, Yun Chai, Aliya Tiemuer,Yuxuan Han, H.-Y. Wang*, Yi Liu*, Frequency upconversion luminescence:New frontiers in bioapplications, Coord. Chem. Rev., 2023, 496, 215379.

3.       Zhao C., Zhou F., Lu K. Yang S., TanB., Sun W., Shangguan L., Wang H.-Y.*, Liu Y.*, Near-infraredfluorescent probe for in vivo monitoring acetylcholinesterase activity. Sens.Actuators B: Chem. 2022, 360, 131647.

4.       Liu W., Yao X., Zhu W., Wang J.,Zhou F., Qian X., Tiemuer A., Yang S., Wang H.-Y.*, Liu Y., Azo-BasedHypoxia-Responsive Self-Assembly Near-Infrared Fluorescent Nanoprobe for InVivo Real-Time Bioimaging of Tumors. ACS Appl. Bio Mater.2021,4, 3, 2752–2758.

5.       Yu H.,Sun W., Tiemuer A., Zhang Y., Wang H.-Y. *, Liu Y.*,Mitochondria targeted near-infrared chemodosimeter for upconversionluminescence bioimaging of hypoxia.Chem. Commun., 2021,57, 5207-5210.

6.        Qian X., Zhu W., Yu H., Xu Y., Liu W., Wang H.-Y. *, LiuY.*, Mitochondria-targeted near-infrared fluorescent probe for monitoring of aCopper(I) in living cells and In vivo.Dyes and Pigments, 2021, 194,109561.

7.       Zhu W.,Qian X., Wang J., Yu H., Liu W., Wang H.-Y.*, Liu Y.*, Near-infraredfrequency upconversion probes for monitoring glutathione S-transferase toevaluate acute liver injury. Sens. Actuators B: Chem.2021, 347,130640.

8.       Zhu W., Yu H., Qian X., Lu K., Zhao C., Zhang Y., Wang H.-Y.*, Liu Y.*, Near-infraredfrequency upconversion probe for revealing the relationship between glutathioneS-transferase and drug-resistance. Anal. Chim. Acta. 2021, 1181, 338920

9.        WangH.-Y., Kasianowicz J. J., Robertson, J.W.F., PosterL. D., and Ettedgui, J., A Comparison of Ion Channel Current Blockades Causedby Individual Poly (ethylene glycol) Molecules and PolyoxometalateNanoclusters.  The Euro. Phys. J. E.2019,42 (6),83.

10.     Wang H.-Y., ZhangH., Chen S., Liu Y.*, Fluorescein-Inspired Near-Infrared Chemodosimeter forLuminescence Bioimaging. Current med. Chem.2019, 26 (21),4029-4041

11.       Wang H.-Y., Ettedgui, J., Forstater, J.H.,Robertson, J.W.F., Reiner J. E., Zhang H., Chen S.,Kasianowicz, J.J. Determining the physical properties ofmolecules with nanometer-scale pores. ACSSens.2018, 3, 251-263.

12.      Liu Y.,Yao X.-F. & Wang H.-Y.*, ProteinDetection Though Single Molecule Nanopore. Chin.J. Anal. Chem.2018, 46,6, e1838-e1846.

13.      Wang, H.-Y.,Song, Z.-Y., Zhang, H.-S., & Chen, S.-P. Single-molecule analysis of lead(II)-binding aptamer conformational changes in an α-hemolysin nanopore, andsensitive detection of lead (II). Microchim.Acta2016, 183,1003-1010.

14.      Wang, H.-Y.,Gu, Z., Wang, J., & Long, Y.-T. Analysis of a single α-synucleinfibrillation by the interaction with a protein nanopore. Analy. Chem.2013, 85,8254-8261.

15.      Wang, H.-Y.,Li, Y., Qin, L.-X., Heyman, A., Shoseyov, O., Willner, I., Long, Y.-T., &Tian, H. Single-molecule DNA detection using a novel SP1 protein nanopore. Chem. Commun.2013, 49, 1741-1743.

16.      Wang, H.-Y.,Ying, Y.-L., Li, Y., Kraatz, H.B., & Long, Y.-T. Nanopore analysis ofβ-amyloid peptide aggregation transition induced by small molecules. Anal. Chem.2011, 83, 1746-1752.

17.      Wang, H.-Y.,Ying, Y.-L., Li, Y., & Long, Y.-T. Peering into Biological Nanopore: APractical Technology to Single‐Molecule Analysis. Chem. An Asian J.2011, 5, 952-1961.

18.      LiuY., Wang S., Ma Y., J Lin, Wang H.-Y.,Gu Y., Chen X., Huang P. Ratiometric photoacoustic molecular imaging formethylmercury detection in living subjects. AdvancedMater. 2017, 29, 1606129.

19.      Kasianowicz,J.J., Balijepalli, A.K., Ettedgui, J., Forstater, J.H., Wang, H.-Y., Zhang, H.,& Robertson, J.W.F.  Analyticalapplications for pore-forming proteins. Biochim.Biophy. Acta – Biomembran.2016, 1858, 593-606.

20.      Ying,Y.-L., Wang, H.-Y. Sutherland, T.C. & Long, Y.-T. Monitoring of anATP‐Binding Aptamer and its Conformational Changes Using an a-HemolysinNanopore. Small2011, 1, 87-94.

21.      Liu,Y., Ying, Y.-L., Wang, H.-Y., Cao, C., Li, D.-W., Zhang,W.-Q., & Long, Y.-T. Real-time monitoring of the oxidative response of amembrane–channel biomimetic system to free radicals. Chem. Commun.2013, 49, 6584-6586.

22.      Liu,T., Bao, C., Wang, H.-Y., Lin, Y., Jia, H., & Zhu, L.Light-controlled ion channels formed by amphiphilic small molecules regulateion conduction viacistransphotoisomerization. Chem. Commun.2013, 49, 10311-10313.

23.       喻皓,汪海燕,龙亿涛基于LabVIEW的纳米通道单分子检测系统,授权专利号:ZL2010 2 0169643.6



Professional Experience

Guest Editor of Results in Chemistry


Teaching

2020.01-2020.12, 项目主持人,中央高校基本业务费基础科研扶持项目-理工类:基于纳米孔的生物仿生界面机械性能研究(2242020K40221

2014.09-2016.12, 项目主持人中国博士后科学基金第56批一等资助项目:纳米通道用于核酸适配体单分子识别行为研究(2014M560670

2021.01-2024.12  项目参与人,国家自然科学基金面上项目:固态纳米孔核酸检测的关键技术和机理 (52075099)



Research Interests

喻皓,汪海燕,龙亿涛等基于LabVIEW的纳米通道单分子检测系统,授权专利号:ZL 2010 2 0169643.6

Refereed Journals
Other Professional Activities
Selected Publications
Research Projects
Patents and Applications